Virology, Emerging Diseases & vaccines

Viral Haemorrhagic Fever

Viral haemorrhagic pyrexia or fever (VHFs) are a group of febrile illnesses caused by RNA viruses from several viral families. These highly infectious viruses lead to a potentially lethal disease syndrome characterized by pyrexia, malaise, regurgitating, mucosal and gastrointestinal (GI) bleeding, oedema, and hypotension. Arenaviridae, Filoviridae, Bunyaviridae, Flaviviridae, and Rhabdoviridae are the families that cause haemorrhagic pyrexia. The viruses that cause VHF are distributed over much of the globe. Each virus is associated with 1 or more vector species or nonhuman host, which restricts the virus and hence the initial contamination to the areas are inhabited by these species. The diseases caused by these viruses are visually perceived in people living in or having visited these areas. For these enzootic diseases humans are incidental hosts; however, person-to-person transmission of some viruses can result in sizably voluminous human outbreaks.Viral haemorrhagic pyrexia or fever (VHFs) are a group of febrile illnesses caused by RNA viruses from several viral families. These highly infectious viruses lead to a potentially lethal disease syndrome characterized by pyrexia, malaise, regurgitating, mucosal and gastrointestinal (GI) bleeding, oedema, and hypotension. Arenaviridae, Filoviridae, Bunyaviridae, Flaviviridae, and Rhabdoviridae are the families that cause haemorrhagic pyrexia. The viruses that cause VHF are distributed over much of the globe. Each virus is associated with 1 or more vector species or nonhuman host, which restricts the virus and hence the initial contamination to the areas are inhabited by these species. The diseases caused by these viruses are visually perceived in people living in or having visited these areas. For these enzootic diseases humans are incidental hosts; however, person-to-person transmission of some viruses can result in sizably voluminous human outbreaks.