Virology, Emerging Diseases & vaccines

Current Trends and Research In Virology

In general,Virology deals with virus-like agents and viruses. Their classification,structure,evolution, their way of infecting and exploiting cells for viral reproduction,viral diseases,isolation techniques and culturing them and also their application in therapy and research. The following are some current research works:

a.   Cloning and rescue of the genome bombyx mori bidensovirus and characterization of a recombinant virus. In this Bombyxmori bidensovirus  has a potential tool as an expression vector and in biological pest control.

b.   Development and Evaluation of non-ribosomal random PCR and next generation sequencing based assay for detection and sequencing of hand,foot, and mouth disease pathogens. Across the Asia-Pacific region hand,foot and mouth disease has become a major public health problem which occurs due to enterovirus A71 and cocksackievirus A6.

c.   Important role of N108 residue in binding of  bovine-foamy virus  transactivator Tas to viral prmoters. In this Bovine foamy virus enhances the viral gene transcription by binding to the long terminal repeat promoter and internal promoter.

d.   Isolation of an imported subgenotype B5 strain of human enterovirus A71. In this Enterovirus A71  which is responsible for the outbreaks of hand,foot and mouth disease.

e.   Differences in viral load among human respiratory syncytical virus genotypes in hospitalized children with severe acute respiratory infections. Here,It is a viral etiology of lower respiratory tract infections such as pneumonia,bronchiolitis.