Bernard Middleton
In collaboration with Synergy Pharmaceuticals Pty Ltd, NSW, Australia.
Biography
Dr Bernard Lucas Middleton, is an infectious diseases physician, scientist and clinical virologist internationally acknowledged for his research on the immunobiology of the herpes virus. His work on microbicide development, and alternative antiviral therapy has been much of his recent principal focus. He was a member of the Centre for HIV and Hepatitis Virology, an institute aimed to combat the impact of HIV and hepatitis. Dr Middleton has previously worked as a physician as a General Practitioner in his earlier years. He then assumed a positon with the State laboratory in Virology. Over the past 20 years he has generated many integral discoveries relating to HSV. His research has been instrumental in defining HSV infections and cell to cell interactions with host immune cells. Specifically focusing on the sacral ganglion and the trigeminal ganglion nerve points, being the initial target infection. Bringing to light new treatments which highlight the process of activation and regulation of macrophages and T Cell applications. His research served to develop a treatment (e.g. 5 core compounds) that aims at the source of infection to eliminate HSV cell to cell infection and viral envelope cessation. His collaborative work on recent studies have made key contributions to human immunology and neurobiology of HSV.