Khaled A Habeb
Baghdad University, Iraq
Title: Phylogenetic analyses of the RpRd&Vp1 overlap region C and RpRd region A of the detected Norovirus genomes in Baghdad province
Biography
Biography: Khaled A Habeb
Abstract
Noroviruses (NoVs) are the most commonly recognized foodborne viral infection and second only to Rotavirus (RV) as a cause of severe diarrhea in children. The high burden of infection is because of their stability in the extreme environment condition, diversity of strains and low infectious dose ranging between 10-100 virus particles which are enough to infect individual. Nucleotide sequence and phylogenetic analysis of the junction of open reading frame one (ORF1) and the open reading frame two (ORF2) and fragments of 60/81 (74.07%) positive samples results found that the appearance of five genotypes: GGII.4, GGII.2, GGII.17, GGI, GGI.3 ACCESSION KU291998.1; KU292999.1; KU292001.1: ACCESSION KU292002.1; KU292003.1; KU292004.1; KU292005.1; KU744839.1. The NVGII.4 was the most dominant strain with frequency percentage 61.6% and the higher frequency percentage 50% was belongs to the recombinant. It has been suggested that recombination could be an important mechanism by which GII.4 remains persistent in human population.