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Rahul Hajare

Indian Council of Medical Research

Title: Why Tall individuals More Prone to Cancer in India

Biography

Biography: Rahul Hajare

Abstract

Tall individuals are at increased risk of almost all cancers, "But skin cancers such as melanoma show an unexpectedly strong relationship to height. This may be because the hormone IGF-1 is at higher levels in taller adults." IGF-1 is a growth factor that is particularly important in early development, but IGF-1 has also been linked to a higher rate of cell division in tall adults [3]. "If cells divide more often, then that adds to cancer risk."If skin cells are dividing more rapidly in tall people due to high levels of IGF-1, then this could account for the increased risk for melanoma." Of the 18 cancers scored in both sexes, Nunney found only four showed no significant increase with height in either sex: pancreas, esophagus, stomach, and mouth. "It is possible that these cancers are more strongly associated with environmental factors."It has, too, that in these tissues cell numbers do not scale with body size but this seems unlikely." Nunney explained that two factors cause increased cancer risk: one is having more cells; the other is having more cell divisions. If double the cells, double the cancer risk. ”If double the number of cell divisions, more than double the cancer risk. Living a long time is the worst thing to do if want to avoid cancer.