Shanghai Tech University,
Dr. Zhaocai Zhou obtained his Ph.D. degree in University of Science and Technology of China, 2004; and received his postdoctoral training in Brandeis University, and University of Pennsylvania, USA, 2004–2008. He joined the Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences in 2009, and become a professor of Shanghai Tech University in 2015. His primary research interest is to understand the signaling mechanism of tumorigenesis and tumor-related immune regulation. His recent work focuses on Hippo/MST signaling pathway and macrophage plasticity.
Our primary research interest is to understand the principle of immune responses and tumor immunology at multiple levels (Figure 1). We combine biochemical and structural analyses with cell signaling, animal models and clinical relevance to explore the function and molecular mechanisms of protein/DNA complexes and pathways that are critical for both immunity and tumorigenesis (Figure 2). In addition to dissecting the nature of these fundamental physiological or pathological processes, we also aim to further discover new drug targets and design novel therapeutic strategies for disease treatment.