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10th World Congress on Virology and Mycology

Singapore City, singapore

Palayakotai Raghavan

Palayakotai Raghavan

Nanorx Inc., USA

Title: Metadichol® and infectious diseases: One process many diseases, many possible cures

Biography

Biography: Palayakotai Raghavan

Abstract

Metadichol (US Patent 8,722,093) is a Nano emulsion of long-chain alcohols found in many foods. It is commonly called Policosanol and is present in foods such as rice, sugar cane, wheat, and peanuts. Metadichol acts on Nuclear Vitamin D receptors (VDR) (US Patent 9,006,292) that are present in cells throughout the body to stimulate the immune system and inhibit a variety of disease processes, resulting from viral infection.

We tested for antiviral activity of Metadichol® in Vero and MDCK cells infected with Influenza A, H1N1, Human Respiratory Syncytial virus, Dengue, Chikungunya and. Ebola, Marburg. In addition, we tested the efficacy of Metadichol® in preventing cell death caused by Adenovirus, Tacaribe Mammarena virus, Rift Valley Fever virus, SARS coronavirus, Japanese Encephalitis virus, West Nile virus, and Yellow Fever virus.  In the in vitro assays, Metadichol showed no cytotoxicity and strongly inhibited cell death caused by each of the viruses tested.

Studies with Zucker diabetic rats showed it was an effective ICAM-1 and TNF-alpha and NFKB-1 inhibitor. ICAM-1 is the same receptor molecule used by the vast majority of bacteria and viruses.

Infectious diseases kill more people worldwide than any other single cause. They represent a major health problem, both regarding morbidity and mortality.  Infectious diseases are disorders caused by pathogens

Metadichol is a safe and effective inhibitor of enveloped viruses in humans. Since it is known to bind to the vitamin D receptor (VDR) (US Patent 9,006,292), its mechanism of action likely involves the competitive displacement of virus particles from VDR’s on host cell membranes. Because it consists of natural components of common foods and has no known negative side effects, Metadichol has the potential to serve as a novel, broad-spectrum antiviral treatment for Dengue, Ebola, Zika, H1N1, SARS, Chikungunya and other enveloped viruses.