Human and Aquatic viromes

The virome is the community of viruses that populate an organism or ecosystem at any given time. This includes the “core” set of commensal viruses that do not give rise to clinical symptoms or viremia, combined with any acute or persistent infections that may be present. viral meta genomics is the method in which nucleic acid is isolated directly from environmental samples  and sequenced without culturing or cloning. These methods permit not only the discovery of a wider range of viral pathogens, but also a broader assessment of the human virome in the absence of clinically recognized disease. According to two global surveys of the ocean virome, which focused mainly on DNA viruses infecting bacteria, have suggested that marine viruses, particularly phages are highly diverse and can exhibit distinctive biogeographic pattern have revealed a diverse array of DNA phages (e.g., Microviridae, Myoviridae, Podoviridae, and Siphoviridae) in marine environments and that local environmental conditions play an important role in structuring their diversity, little is known about the diversity of RNA viruses and eukaryotic viruses in the oceans and their global transport and disease potential .A metagenome is the total genetic(DNA and RNA) sequence derived from a viral community .Mathematically,  the structure of a community may be represented by a graph whose functional form reflects the relative abundance distribution of its members.

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