Herpes viruses

Herpes is a infection and infected with the herpes simplex virus, can be due to either herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2). HSV-1 is mostly transmitted by oral to oral contact to cause infection in or around the mouth. HSV-2 is almost completely sexually transmitted, causing infection in the genital or anal area .based on that they are known as oral and gential herpes. HSV-1 can also be transmitted to the genital area through oral-genital contact to cause genital herpes.Both infections are generally asymptomatic but can cause mild symptoms or painful blisters or ulcers at the site of infection.

                Varicella-zoster virus and herpes simplex virus are the two human members of alphaherpes subfamily. While most of VZV genes are highly conserved with those of HSV,the genes in these two viruses often have different promoter regions and the pattern of gene expression during latency is very different (because single in HSV whereas six gene in VSV).

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