Hepatitis A virus

It is a infectious agent and that cause the disease Hepatitis A. Earlier it  is classified as enterovirus type 72 because of its physical and chemical chracteristics related to entero virus, but it differs in nucleotide and aminoacid sequences and sizes of HAV proteins are dissimilar and they replicate very slowly without cytopathic effect in cell culture and they resistant to temperatures and drugs which can inactivate many picornaviruses and stable to pH-1,so due these reasons they was classifised into new genus, Hepatovirus with in the family Picornaviridae. An HAV isolate distinguished from HAV isolates is known as a strain. Viruses recovered from different locations often represent differents strains, whereas viruses from individuals from outbreak usually represent the same strain. Viruses from two or more locations can represent same strainor more than one strain may be present at a given location and time. It occurs irregularly and in epidemics worldwide, with a tendency for cyclic recurrences. It is one of the most frequent causes of foodborne infection.

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